Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Feb 26;51(5):1643–1648. doi: 10.1128/AAC.01282-06

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2007, American Society for Microbiology

PMC Copyright notice

FIG. 4. — Quinolone-mediated DNA cleavage by M. leprae DNA gyrase. Supercoiled pBR322 DNA (0.4 μg) was incubated with the M. leprae GyrA (300 ng) and GyrB (250 ng) proteins in the presence of ATP and of moxifloxacin (MXF), gatifloxacin (GAT), or ofloxacin (OFX) at the indicated concentration (in μg/ml). After addition of SDS and proteinase K, the DNA samples were analyzed by electrophoresis in 1% agarose. Lane a, supercoiled pBR322 DNA; R, N, and S, relaxed, nicked, and supercoiled DNA, respectively.