Table 2.

Shows the frequency (%) of CsA assay methods used in an Australasian survey¹⁹, compared with the International CsA Proficiency Testing Program^†, and the CAP Program^††, as related to the assay bias compared with a specific HPLC method ⁶⁷.

^§as described by Steimer ⁶⁷

^*total of 106% reflects that some labs had changed methods during year 2000 and so counted twice.

^†International Cyclosporin Proficiency Testing program, Analytical Services International, London, www.bioanalytics.co.uk.

^††Data both published¹⁰ and by personal communication from Dr Steven Soldin, Washington DC, USA.

^¶The Steimer paper ⁶⁷ described the original Cedia^® method as having a bias of 18%; however, the current version, Cedia Plus^®, compares more favourably with EMIT^® and Cyclotrac^® mRIA.