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. Author manuscript; available in PMC: 2008 Feb 3.
Published in final edited form as: Brain Res. 2006 Dec 13;1131(1):68–76. doi: 10.1016/j.brainres.2006.11.018

Table 2.

Ratios of dopamine uptake inhibition potency-to-binding affinity constants for DAT ligands at WT DAT CHO cells as a function of cell passage number

DUIP:Affinity Ratio Cell Passage
Low Medium High
Cocaine 4.0 5.3 5.9
Mazindol 2.9 3.8 4.7
Methylphenidate 4.8 8.8 7.8
Benztropine 3.0 4.6 4.5
(+)-Amphetamine 1.3 1.6 1.6