FIG. 2.

Disruption of ydcQ suppresses lethality of rpoE::cam and downregulates degP transcription. (A) Genetic organization of the ydcQ locus and localization of various insertion elements and antibiotic resistance markers. Arrows indicate the direction of transcription. (B) Disruption of ydcQ but not of ydcR reduces expression of degP′-lacZ⁺ and suppresses lethality of rpoE::cam. Relative levels of LacZ expression from the degP′-lacZ⁺ fusion on lactose MacConkey agar are indicated with “+” signs. If a mutation is able to suppress the lethality of rpoE::cam, a “+” is shown on the right column, but if a mutation is not able to suppress lethality, a “−” is shown.