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Loss of YdcQ downregulates production of outer membrane vesicles. Western blot analysis of the outer membrane proteins OmpA and LamB, periplasmic protein MBP, and outer membrane lipid LPS shows that although the loss of YdcQ function in NR905 does not alter the levels of these envelope components in whole cells, it reduces the amount of outer membrane vesicles present in culture supernatants compared to the wild-type strain MC4100.
