TABLE 2.
B. anthracis orthologs of B. subtilis sporulation and germination genes identified in the TraSH screen
| Gene | Descriptiona | P valueb |
|---|---|---|
| BA1048 | ABC transporter, ATP-binding protein EcsA | 0.0193 |
| BA4151 | Cytochrome c oxidase, subunit IVB | 0.0191 |
| BA5050 | Cytochrome d ubiquinol oxidase, subunit I | 0.0123 |
| BA3938 | Dipicolinate synthase, B subunit | 0.04 |
| BA4637 | GTP pyrophosphokinase, RelA | 0.0439 |
| BA1510 | Negative regulator of competence MecA, putative | 0.0107 |
| BA0424 | Polysaccharide deacetylase, PdaA | 0.0175 |
| BA0819 | Germination protein GerN | 0.00571 |
| BA1639 | Germination protein GerN | 0.0267 |
| BA4986 | Spore germination protein GerHC | 0.0444 |
| BA0634 | Spore germination protein GerKB | 0.00841 |
| BA0709 | Spore germination protein GerLA | 0.000711 |
| BA0710 | Spore germination protein GerLB | 0.00452 |
| BA0763 | Spore germination protein GerYA | 0.0328 |
| BA1492 | Spore maturation protein | 0.00565 |
| BA4546 | Spore protease | 0.00295 |
| BA5730 | Sporulation initiation inhibitor protein Soj | 0.0399 |
| BA2644 | Sporulation kinase B | 0.00153 |
| BA4530 | Sporulation protein | 0.00715 |
| BA4394 | Stage 0 sporulation protein A | 0.0335 |
| BA5581 | Stage 0 sporulation protein F | 5.28E-05 |
| BA4688 | Stage II sporulation protein B, putative | 0.00279 |
| BA5528 | Stage II sporulation protein D | 0.024 |
| BA0061 | Stage II sporulation protein E | 0.00533 |
| BA2068 | Stage II sporulation protein P | 0.0365 |
| BA5263 | Stage III sporulation protein J | 0.0352 |
| BA1530 | Stage IV sporulation protein A | 3.02E-05 |
| BA4396 | Stage IV sporulation protein B | 0.00333 |
| BA4643 | Stage V sporulation protein B | 0.00298 |
| BA0054 | Stage V sporulation protein B, putative | 0.00863 |
| BA4050 | Stage V sporulation protein E | 0.00438 |
a
Gene descriptions were obtained from The Institute for Genome Research genome annotation (17).
b
Values were calculated by comparing the mean hybridization signal ratio (preselection/postselection) to 1 using the GeneSpring software as described in the text.