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Mouse colonization densities with H. pylori strain X47 and antisense constructs in CJB/6J micea
| Strain | No. of mice infected/total no. of mice | No. of CFU/g stomach ± SD |
|---|---|---|
| Mock (1× PBS) | 0/5 | 0 |
| WT X47 | 5/5 | (1.01 ± 0.13) × 107 |
| X47rdxA::aphA3 | 5/5 | (1.03 ± 0.30) × 107 |
| X47rdxA::AS1563-2 | 5/5 | (1.00 ± 0.05) × 107 |
Five mice each were infected with strain X47, X47rdxA::aphA3, or X47rdxA::AS1563-2, and 3 weeks postinfection, bacterial load was determined (CFU/g stomach) as described in the text.
