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. 2006 Nov 22;189(9):3573–3580. doi: 10.1128/JB.01083-06

FIG. 1.

FIG. 1.

Pathway for polymerization of PBG and modification of porphyrinogen's side chain in the biosynthesis of tetrapyrroles. The acetate, propionate, and vinyl groups are denoted A, P, and V, respectively. Without the inversion of the D-ring, hydroxymethylbilane cyclizes to form symmetric urogen I. The enzymes responsible for the polymerization of PBG and modification of porphyrinogen's side chains, PBGD, UROD, UPMT, and CPOX, are described in the text. The enzyme UROD, which is the focus of this study, is underlined. The figure was generated using ChemWindow 6.0.