Table 2.
Partial correlations of cancer incidence (INCID) distances with ethnohistoric (ETH), genetic (GEN), and geographic (GEO) distances in Europe
| ICD no. | Cancer |
r(INCID,ETH.GEN,GEO)
|
r(INCID,GEN.ETH,GEO)
|
||
|---|---|---|---|---|---|
| Males | Females | Males | Females | ||
| 140 | Lip | −0.0146 | −0.0129 | 0.0604† | 0.0882‡ |
| 141 | Tongue | −0.0193 | 0.0041 | 0.0616† | 0.0141 |
| 142 | Salivary gland | 0.0061 | −0.0075 | −0.0003 | 0.0289 |
| 143–145 | Mouth | −0.0263 | −0.0057 | 0.0857‡ | 0.0339* |
| 146 | Oropharynx | −0.0225 | 0.0120 | 0.0656† | −0.0315 |
| 147 | Nasopharynx | −0.0126 | −0.0247 | 0.0476† | 0.0720* |
| 148 | Hypopharynx | −0.0137 | −0.0238 | 0.0529* | 0.0701† |
| 149 | Unspecified pharynx | −0.0084 | −0.0002 | 0.0365* | 0.0479 |
| 150 | Esophagus | −0.0428 | −0.0165 | 0.1342‡ | 0.0494‡ |
| 151 | Stomach | −0.0186 | −0.0156 | 0.0922‡ | 0.0687‡ |
| 152 | Small intestine | 0.0047 | 0.0086 | −0.0057 | −0.0389 |
| 153 | Colon | −0.0153 | −0.0281 | 0.0708‡ | 0.1127‡ |
| 154 | Rectum | −0.0103 | −0.0048 | 0.0344 | 0.0222 |
| 155 | Liver | −0.0196 | −0.0380 | 0.0567† | 0.1061‡ |
| 156 | Gall bladder | −0.0051 | −0.0076 | −0.0040 | 0.0069 |
| 157 | Pancreas | −0.0119 | −0.0114 | 0.0217 | 0.0222 |
| 158 | Peritoneum | −0.0118 | −0.0053 | 0.0303* | 0.0202 |
| 160 | Nose/sinuses | −0.0095 | 0.0000 | 0.0416* | 0.0013 |
| 161 | Larynx | −0.0309 | −0.0022 | 0.0996‡ | 0.0160 |
| 162 | Bronchus/trachea/lung | −0.0106 | −0.0155 | 0.0239 | 0.0290† |
| 163 | Pleura | 0.0078 | 0.0025 | 0.0045 | −0.0010 |
| 164 | Other thoracic | −0.0048 | −0.0132 | 0.0098 | 0.0582† |
| 170 | Bone | −0.0010 | −0.0103 | 0.0279 | 0.0508† |
| 171 | Connective tissue | 0.0026 | −0.0005 | 0.0085 | 0.0285† |
| 172 | Melanoma | 0.0173 | 0.0030 | −0.0285 | −0.0099 |
| 173 | Other skin | 0.0185 | 0.0183 | −0.0328 | −0.0393 |
| 174 | Breast | −0.0044 | −0.0114 | 0.0624† | 0.0704‡ |
| 180 | Cervix uteri | −0.0020 | −0.0116 | ||
| 181 | Chorionepithelioma | −0.0195 | 0.1259‡ | ||
| 182 | Corpus uteri | −0.0102 | 0.0364 | ||
| 183 | Ovary | −0.0226 | 0.0320* | ||
| 184 | Other female genital | −0.0018 | 0.0068 | ||
| 185 | Prostate | 0.0047 | 0.0055 | ||
| 186 | Testis | −0.0011 | 0.0079 | ||
| 187 | Penis | −0.0073 | 0.0295 | ||
| 188 | Bladder | −0.0133 | −0.0051 | 0.0782‡ | 0.0304* |
| 189 | Other urinary | −0.0031 | −0.0038 | 0.0219 | 0.0066 |
| 190 | Eye | 0.0134 | 0.0058 | −0.0362 | −0.0054 |
| 191–192 | Brain/nervous system | 0.0085 | 0.0147 | −0.0168 | −0.0297 |
| 193 | Thyroid | 0.0027 | 0.0123 | 0.0115 | −0.0072 |
| 194 | Other endocrine | 0.0171 | 0.0108 | −0.0382 | −0.0424 |
| 200+202 | Non-Hodgkin's lymphoma | 0.0069 | −0.0073 | 0.0077 | 0.0597† |
| 201 | Hodgkin's disease | −0.0211 | −0.0018 | 0.0733‡ | 0.0213 |
| 203 | Multiple myeloma | −0.0157 | 0.0098 | 0.0683‡ | −0.0137 |
| 204 | Lymphatic leukemia | −0.0003 | 0.0061 | 0.0047 | 0.0157 |
| 205 | Myeloid leukemia | −0.0072 | −0.0045 | 0.0468* | 0.0219* |
| 206 | Monocytic leukemia | 0.0021 | −0.0051 | 0.0165 | −0.0009 |
| 207 | Other leukemia | 0.0040 | −0.0019 | −0.0004 | 0.0203 |
| 208 | Unspecified leukemia | 0.0076 | 0.0112 | 0.0048 | −0.0124 |
| 209 | Myelofibrosis | 0.0030 | 0.0031 | 0.0635 | 0.1747* |
| Mean r | −0.0057 | −0.0046 | 0.0312 | 0.0269 | |
| Combined P | 1.00000 | 1.00000 | 0.00000‡ | 0.00000‡ | |
ICD 209 averages based on three genetic systems only. All other averages based on minimally 15 systems (males) or 14 systems (females). *, 0.01 < P ≤ 0.05; †, 0.001 < P ≤ 0.01; ‡, P ≤ 0.001.