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Type 2 capsule structure and genetic locus. (A) Structure of the repeat unit. Synthesis of the backbone initiates by addition of Glc-1-P to a polyprenol acceptor. (B) Genetic organization of the type 2 capsule locus (34). S. pneumoniae capsule loci are flanked by dexB upstream and aliA (also referred to as plpA) downstream. The arrow indicates the putative transcript containing cps2A to cps2O.
