Table 1.
Baseline | High salt | Low salt | P* (high-vs. low-salt) | |
24-hour SBP (mmHg) | 139±13.3 | 136±12.7 | 131±11.1 | <0.0001 |
24-hour DBP (mmHg) | 86.3±7.4 | 85.0±7.0 | 82.3±6.6 | 0.004 |
24-hour HR (bpm) | 72.3±9.0 | 67.7±8.4 | 69.1±7.9 | 0.08 |
Daytime SBP (mmHg) | 144±13.2 | 141±12.8 | 135±11.7 | <0.0001 |
Daytime DBP (mmHg) | 90.6±7.8 | 89.2±7.3 | 86.9±6.9 | 0.02 |
Daytime HR (bpm) | 76.1±9.7 | 67.7±8.4 | 73.8±9.1 | 0.04 |
Night-time SBP (mmHg) | 129±14.4 | 128±13.6 | 121±11.5 | <0.0001 |
Night-time DBP (mmHg) | 77.5±7.9 | 76.4±7.6 | 73.0±7.9 | 0.002 |
Night-time HR (bpm) | 64.4±9.0 | 58.4±8.2 | 59.5±6.9 | 0.17 |
Body weight (kg) | 79.5±11.2 | 77.4±10.7 | 77.3±10.6 | 0.43 |
Urine-Na+ (mmol/24h) | 165±67.4 | 140±39.5 | 50.7±17.3 | <0.0001 |
Urine-K+ (mmol/24h) | 75.0±22.9 | 50.8±11.3 | 50.9±14.1 | 0.94 |
Urine-Crea (mmol/24h) | 13.1±3.3 | 12.3±2.7 | 12.2±3.0 | 0.65 |
Serum-Na+ (mmol/L) | 140±1.8 | 141±1.5 | 139±1.7 | <0.0001 |
Serum-K+ (mmol/L) | 3.7±0.26 | 3.6±0.25 | 3.7±0.30 | 0.21 |
Serum-Crea (mmol/L) | 78.4±12.8 | 80.4±12.8 | 84.1±12.6 | 0.001 |
Plasma renin (mU/L) | 15.3±9.4 | 17.4±11.2 | 32.4±18.4 | <0.0001 |
Refer to individual change of variable on high- as compared with on low-salt (i.e. variable Δ-value). SBP, systolic blood pressure; DBP, diastolic blood pressure; Crea, Creatinine; HR, heart rate.