Table 2. Salt-induced changes in blood pressure and baseline P-renin and Nt-proANP in different genotype carriers.
| rs4149601 genotype variants | ||||
| GG (n = 16) | GA (n = 20) | AA (n = 3) | P-value; GG vs GA or AA | |
| Δ24SBP(mmHg) | 6.5(3.0–13) | 6.5(0.0–10) | 2.0(−8.0–15) | 0.315 |
| Δ24DBP(mmHg) | 1.5(−1.0–9.75) | 3.5(−0.5–5.75) | −1.0(−5.0–8.0) | 0.703 |
| ΔDSBP(mmHg) | 6.5(2.0–14.5) | 6.0(−2.0–9.0) | 5.0(−6.0–7.0) | 0.343 |
| ΔDDBP(mmHg) | 2.0(−3.0–9.75) | 2.0(−1.0–4.75) | 1.0(−5.0–3.0) | 0.921 |
| ΔNSBP(mmHg) | 11.5(2.25–15) | 6.0(0.25–9.0) | −3.0(−15–30) | 0.107 |
| ΔNDBP(mmHg) | 4.5(1.25–9.5) | 4.0(−2.75–7.0) | −4.0(−8.0–16.0) | 0.196 |
| P-renin(mU/L) | 10.5(6.5–15.8) | 18.0(10.0–28.0) | 9.0(2.0–25.0) | 0.045 |
| Nt-proANP(pmol/L) | 510(419–803) | 510(422–646) | 620(440–786) | 0.641 |
| rs2288774 genotype variants | ||||
| CC (n = 12) | CT (n = 14) | TT (n = 13) | P-value; CC vs CT or TT | |
| Δ24SBP(mmHg) | 7.5(3.0–16.5) | 4.0(−1.25–7.75) | 7.0(2.5–12) | 0.168 |
| Δ24DBP(mmHg) | 4.5(−0.5–8.25) | 1.0(−2.0–4.0) | 3.0(−1.0–6.5) | 0.221 |
| ΔDSBP(mmHg) | 7.5(2.75–19) | 3.5(−2.0–7.0) | 7.0(0.5–11.0) | 0.178 |
| ΔDDBP(mmHg) | 3.0(0.25–9.75) | −0.5(−1.5–4.0) | 3.0(−2.0–5.5) | 0.188 |
| ΔNSBP(mmHg) | 9.0(0.25–15) | 4.5(−1.0–8.75) | 9.0(3.5–12.5) | 0.443 |
| ΔNDBP(mmHg) | 5.5(−2.75–8.0) | 3.5(−2.25–7.0) | 5.0(2.0–7.5) | 0.845 |
| P-renin(mU/L) | 10.5(6.5–19.5) | 14.0(9.0–21.5) | 14.5(6.75–28.75) | 0.185 |
| Nt-proANP(pmol/L) | 659(438–844) | 559(359–732) | 489(436–599) | 0.150 |
Blood pressure change in low versus (vs) high salt intake; Δ24SBP, delta 24-hour systolic blood pressure; Δ24DBP, delta 24-hour diastolic blood pressure; ΔDSBP, delta daytime systolic blood pressure; ΔDDBP, delta daytime diastolic blood pressure; ΔNSBP, delta night-time systolic blood pressure; ΔNDBP; delta night-time diastolic blood pressure. P-value<0.05 is considered statistically significant. Numbers represent Median(Inter Quartile Range).