Table 3 Predictors of erosions and Larsen score.
Characteristic | Risk of erosions OR (95% CI) | Increase in Larsen score multiplier (95% CI) |
---|---|---|
Age (years) | ||
<50 | 1 (referent) | 1 (referent) |
50–69 | 3.50 (2.24 to 5.74) | 3.74 (1.82 to 7.70) |
⩾70 | 7.39 (4.51 to 12.10) | 8.40 (3.81 to 18.52) |
Sex | ||
Male | 1 (referent) | 1 (referent) |
Female | 0.87 (0.50 to 1.53) | 1.17 (0.75 to 1.84) |
Swollen joints | ||
Lowest tertile | 1 (referent) | 1 (referent) |
Middle tertile | 1.98 (1.03 to 3.82) | 1.41 (0.85 to 2.33) |
Highest tertile | 2.55 (1.31 to 4.95) | 2.00 (1.21 to 3.32) |
Tender joints | ||
Lowest tertile | 1 (referent) | 1 (referent) |
Middle tertile | 2.23 (1.11 to 4.48) | 1.25 (0.74 to 2.09) |
Highest tertile | 1.10 (0.67 to 1.82) | 1.34 (0.72 to 2.49) |
Rheumatoid factor* | ||
−ve | 1 (referent) | 1 (referent) |
+ve | 1.65 (0.91 to 2.99) | 1.01 (0.63 to 1.63) |
HAQ score | ||
<1 | 1 (referent) | 1 (referent) 1.60 |
⩾1 | 1.51 (1.05 to 2.17) | (1.19 to 2.14) |
CRP | ||
Lower tertile | 1 (referent) | 1 (referent) |
Middle tertile | 0.92 (0.47 to 1.82) | 1.21 (0.70 to 2.08) |
Highest tertile | 1.33 (0.68 to 2.60) | 1.38 (0.81 to 2.37) |
Shared epitope† | ||
Number of copies | 1 (referent) | 1 (referent) |
Any copy | 1.28 (0.71 to 2.30) | 1.26 (0.80 to 1.98) |
CRP, Creative Protein; HAQ, Health Assessment Question
*Shared epitope data available only in 173 subjects.
†Rheumatoid factor available only in 208 subjects.