Table 5 Most common (⩾5%) treatment related adverse events.

Adverse event	Placebo (n = 95)	Exisulind 200 mg (n = 91)	Exisulind 400 mg (n = 95)	p Value*
Abdominal pain	3 (3.2%)	3 (3. 3%)	14 (14.7%)	0.005
ALT increased	1 (1.1%)	1 (1.1%)	8 (8.4%)	0.017
AST increased	1 (1.1%)	1 (1.1%)	8 (8.4%)	0.017
Alkaline phosphatase	2 (2.1%)	2 (2.2%)	7 (7.4%)	0.085
Dyspepsia	4 (4.2%)	4 (4.4%)	5 (5.3%)	0.5
Diarrhoea	3 (3.2%)	3 (3.3%)	5 (5.3%)	0.36

AST, aspartate aminotransferase; ALT, alanine aminotransferase.

*Exisulind 400 mg versus placebo.