Table 3 Relations between genetic instability and tumour location.
| Total | LOH+ | MSI+ | LOH+ and MSI+ | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Epithelium | Stroma | Epithelium | Stroma | Epithelium | Stroma | |||||
| HP | Proximal | 10 | 1/10 | 0/10 | 2/10 | 0/10 | 0/10 | 1/10 | ||
| Distal | 24 | 0/24 | 0/24 | 1/24 | 0/24 | 0/24 | 0/24 | |||
| TA‐L | Proximal | 21 | 2/21 | 2/21 | 2/21 | 0/21 | 0/21 | 0/21 | ||
| Distal | 17 | 3/17 | 0/17 | 0/17 | 2/17 | 0/17 | 0/17 | |||
| TA‐H | Proximal | 19 | 4/19 | 2/19 | 3/19 | 2/19 | 2/19 | 0/19 | ||
| Distal | 32 | 8/32 | 1/32 | 2/32 | 1/32 | 0/32 | 0/32 | |||
| Ca | Proximal | 13 | 0/13* | 3/13 | 5/13† | 0/13 | 2/13 | 1/13 | ||
| Distal | 28 | 16/28* | 2/28 | 0/28† | 1/28 | 7/28 | 1/28 | |||
Proximal: caecum, ascending colon, and transverse colon.
Distal: descending colon, sigmoid colon, and rectum.
HP, hyperplastic polyp; TA‐L, tubular adenoma with low grade dysplasia; TA‐H, tubular adenoma with high grade dysplasia; Ca, adenocarcinoma.
*p<0.05; †p<0.005.