Table 2 Changes in caecal bacterial flora induced by dextran sodium sulphate (DSS) treatment and effects of 1.4‐dihydroxy‐2‐naphthoic acid (DHNA) administration in the DHNA therapy group.
| DHNA therapy protocol | Bacterial counts (log 10 cfu) | |||
|---|---|---|---|---|
| Organism | Normal | DSS (therapy control) | DSS‐DHNA (0.6 mg) | DSS‐DHNA (2.0 mg) |
| Bacteroides | 9.59 (0.21) | 9.38 (0.17) | 9.74 (0.45) | 9.39 (0.2) |
| Lactobacillus | 9.07 (0.33) | 8.01 (0.28) | 9.02 (0.22) | 9.90† (0.19) |
| Bifidobacterium | 8.33 (0.32) | 8.21 (0.34) | 8.45 (0.41) | 8.40 (0.44) |
| Enterobacteriaceae | 6.08 (0.44) | 4.55* (0.23) | 6.30† (0.33) | 5.78† (0.24) |
Results are expressed as log10 cfu, mean (SEM) of caecal contents for 10 mice.
Normal, non‐treated control mice.
*p<0.05 versus normal, †p<0.05 versus DSS treated controls.
DSS‐DHNA: DSS treatment followed by DHNA administration.