Figure 2 Colonic paracellular permeability 72 hours after an acute stress session or BrX‐537A injection (2 mg/kg intraperitoneally) and after pretreatment with the mast cell stabiliser doxantrazole (Dox 10 mg/kg intraperitoneally). Doxantrazole was administered 30 minutes before the stress session or BrX‐537A injection. Values are mean (SD) per cent ⁵¹Cr‐EDTA crossing the epithelial barrier. ***p<0.001 compared with controls; ††p<0.01 compared with doxantrazole vehicle; n = 8 per group. T = time after single stress session or BrX‐537A perfusion.