Table 5 Logistic regression modelling of iron phenotype risk.

	Coefficient	Standard error	Deviance explained (%)	p Value*
Intercept	−5.17	0.89	–	–
Homozygous C282Y	4.86	0.79	84.15 (41.7%)	⩽0.001
Sex	−1.79	0.61	12.72 (6.3%)	0.003
Propensity score	7.31	2.33	11.38 (5.6%)	0.002
Proband group	0.51	0.57	6.66 (3.3%)	0.189†

*p value from a z approximation of the maximum likelihood estimate of each regression coefficient.

All p values are two sided except (†).

Use of a one sided test for the proband group was justified by the prior expectation that relatives in the clinical group should be at a higher risk than relatives in the screened group.