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. 2006 Apr;55(4):450–456. doi: 10.1136/gut.2005.081943

graphic file with name gt81943.f7.jpg

Figure 7 Effect of celecoxib on oesophageal prostaglandin E2 (PGE2) synthetic activity. PGE2 levels were significantly increased in oesophagitis on both days 3 and 21. Celcecoxib (10 mg/kg/day) significantly inhibited the increase in PGE2 levels in oesophagitis. Values are mean (SD) of six experiments. *p<0.001 versus normal oesophagus; **p<0.001. Control = vehicle treated group.