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| Extent | Anatomy | |
|---|---|---|
| E1 | Ulcerative proctitis | Involvement limited to the rectum (that is, proximal extent of inflammation is distal to the rectosigmoid junction) |
| E2 | Left sided UC (distal UC) | Involvement limited to a proportion of the colorectum distal to the splenic flexure |
| E3 | Extensive UC (pancolitis) | Involvement extends proximal to the splenic flexure |
