Table 4 Univariate analysis of relationship between Helicobacter pylori genotyping and histology.
Antrum | Corpus | ||||||||
---|---|---|---|---|---|---|---|---|---|
n | H pylori density | Neutrophil infiltration | Intestinal metaplasia | Atrophy | H pylori density | Neutrophil infiltration | Intestinal metaplasia | Atrophy | |
BabA | |||||||||
Positive | 158 | 2.5 (2.6) | 2.6 (2.5) | 0.7 (0) | 1.7 (1.2) | 2.5 (2.7) | 1.9 (2.1) | 0.3 (0) | 0.6 (0) |
Negative | 42 | 2.1 (2.1) | 1.8 (1.8) | 0.4 (0) | 0.9 (0.6) | 2.0 (1.9) | 1.3 (1.0) | 0.2 (0) | 0.3 (0) |
p value | 0.018 | 0.002 | NS | 0.001 | 0.005 | 0.020 | NS | NS | |
BabB | |||||||||
Positive | 135 | 2.4 (2.5) | 2.4 (2.4) | 0.7 (0) | 1.4 (1.0) | 2.4 (2.3) | 1.8 (2.0) | 0.3 (0) | 0.5 (0) |
Negative | 65 | 2.4 (2.4) | 2.5 (2.4) | 0.7 (0) | 1.6 (1.2) | 2.5 (2.4) | 1.7 (2.0) | 0.3 (0) | 0.6 (0) |
p value | NS | NS | NS | NS | NS | NS | NS | NS | |
SabA | |||||||||
Positive | 116 | 2.4 (2.6) | 2.1 (2.4) | 0.8 (0) | 1.8 (1.3) | 2.3 (2.0) | 1.5 (1.7) | 0.4 (0) | 0.7 (0) |
Negative | 84 | 2.5 (2.5) | 2.9 (2.7) | 0.5 (0) | 1.0 (0.6) | 2.6 (2.8) | 2.2 (2.0) | 0.2 (0) | 0.4 (0) |
p value | NS | <0.001 | 0.056 | <0.001 | 0.017 | <0.001 | 0.049 | 0.047 | |
OipA | |||||||||
Positive | 154 | 2.6 (2.7) | 2.7 (2.5) | 0.8 (0) | 1.6 (1.0) | 2.6 (2.8) | 1.9 (2.0) | 0.3 (0) | 0.6 (0) |
Negative | 46 | 1.9 (1.8) | 1.7 (1.8) | 0.4 (0) | 1.0 (0.9) | 1.9 (2.1) | 1.3 (1.0) | 0.1 (0) | 0.4 (0) |
p value | <0.001 | <0.001 | NS | 0.021 | <0.001 | 0.005 | NS | NS | |
CagA | |||||||||
Positive | 160 | 2.5 (2.6) | 2.6 (2.5) | 0.8 (0) | 1.6 (1.0) | 2.5 (2.7) | 1.9 (2.0) | 0.3 (0) | 0.6 (0) |
Negative | 40 | 2.1 (1.9) | 1.8 (1.9) | 0.2 (0) | 0.9 (0.6) | 2.0 (2.1) | 1.4 (1.1) | 0.1 (0) | 0.3 (0) |
p value | 0.029 | 0.003 | 0.030 | 0.005 | 0.010 | 0.054 | 0.031 | 0.098 |
NS, not significant, p>0.10.
For histological scores (minimum 0 to maximum 5), mean (median) are presented.