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. 2006 Aug;55(8):1084–1089. doi: 10.1136/gut.2005.073262

Table 3 Functional group analysis based on cellular or biological gene ontology terms (GO‐term)12.

Observed Expected Enrichment ratio p Value p‐fdr p‐bonf
Cellular GO‐term
 Cytosolic ribosome (sensu Eukaryota) 15 2.15 6.98 <0.00001 0.00135 0.00674
 Intracellular non‐membrane bound organelle 113 56.23 2.01 <0.00001 0.00135 0.00674
 Ribosome 33 8.22 4.01 <0.00001 0.00135 0.00674
 Vacuole 20 5.55 3.6 <0.00001 0.00135 0.00674
 Large ribosomal subunit 11 2.04 5.39 <0.00001 0.00135 0.00674
 Chromosome 28 11.22 2.5 0.00001 0.00225 0.01348
 Chromosome, pericentric region 9 1.7 5.29 0.00003 0.00578 0.04044
 Spindle 11 2.72 4.04 0.00006 0.01011 0.08088
 Nucleolus 12 4.08 2.94 0.00066 0.09885 0.88968
Biological GO‐term
 Cell proliferation 105 55.28 1.9 <0.00001 0.00733 0.01466
 DNA metabolism 57 26.68 2.14 <0.00001 0.00733 0.01466
 Nucleotide metabolism 23 9.48 2.43 0.00007 0.05131 0.20524
 Macromolecule biosynthesis 63 38.75 1.63 0.00007 0.05131 0.20524
 Nucleotide biosynthesis 18 6.77 2.66 0.00013 0.07623 0.38116

Significance value (p) is corrected for multiple testing by the method of Benjamini‐Hochberg (p‐fdr) and the method of Bonferroni (p‐bonf). Only significantly enriched gene ontology terms with p‐fdr <0.1 are shown.