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. 2006 Aug;55(8):1095–1103. doi: 10.1136/gut.2005.077503

Table 5 Analysis of the first part of the study as a parallel‐group design placebo‐controlled study.

Before citalopram Citalopram 3 weeks Citalopram 6 weeks 3 weeks after citalopram Before placebo Placebo 3 weeks Placebo 6 weeks 3 weeks after placebo
No of days abdominal pain 5.4 (0.3) 4.8 (0.4) 3.7 (0.5)*† 4.0 (0.4)* 5.4 (0.3) 5.3 (0.3) 5.2 (0.3) 5.2 (0.4)
Severity of abdominal pain 7.2 (0.6) 6.2 (0.6) 4.9 (0.7)*† 5.4 (0.8)* 7.8 (0.4) 7.0 (0.4) 7.0 (0.6) 7.2 (0.8)
Worst episode of abdominal pain 7.8 (0.6) 6.6 (0.6)*† 4.9 (0.8)*† 5.4 (0.8) 8.8 (0.3) 8.7 (0.4) 8.5 (0.4) 7.7 (0.9)
No of days with bloating 4.9 (0.5) 4.2 (0.5)* 3.4 (0.4)* 4.2 (0.5) 4.8 (0.5) 4.5 (0.5) 3.8 (0.6) 4.2 (0.6)
Severity of bloating 6.5 (0.8) 5.1 (0.6) 4.7 (0.7)* 5.1 (0.7)* 5.8 (0.7) 5.4 (0.8) 4.8 (0.7) 5.2 (1.0)
Worst episode of bloating 7.2 (0.9) 6.6 (0.6) 6.2 (0.5) 6.1 (0.8) 7.1 (0.8) 6.2 (0.9)* 7.0 (1.0) 6.4 (0.9)*
No of days with incomplete evacuation 3.8 (0.6) 3.2 (0.4)* 3.2 (0.5)* 4.0 (0.5)† 2.6 (0.5) 2.7 (0.4) 2.5 (05) 2.3 (0.4)
Overall severity assessment 7.1 (0.7) 5.7 (0.7)*† 5.0 (0.8)*† 5.4 (0.9)* 7.8 (0.2) 7.7 (0.4) 7.3 (0.5) 6.8 (0.7)
No of days with impact on daily life 5.2 (0.4) 4.4 (0.3)* 3.7 (0.5)* 4.1 (0.5)* 4.9 (0.2) 5.0 (0.2) 4.4 (0.2) 4.5 (0.4)
Severity of impact on daily life 6.5 (0.6) 5.7 (0.7)* 5.1 (0.8)* 6.0 (0.7) 6.9 (0.4) 6.9 (0.4) 6.4 (0.4) 6.6 (0.7)

*Significant compared with run in: p<0.05.

†Significant compared with placebo: p<0.05.

Only those parameters where significance was reached are shown.