Table 2 Cancer risk differences in Peutz‐Jeghers syndrome patients between familial (F) versus isolated (S) cases.
| Sex | No of cancers of each type (% of subgroup) by PJS case type (F or S) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All cancers | Gastrointestinal | Gynaecological | Breast | Other | ||||||
| F | S | F | S | F | S | F | S | F | S | |
| Overall | 27 (21%) | 2 (13%) | 20 (15%) | 2 (13%) | – | – | – | – | 2 (2%) | 0 (0%) |
| p = 0.29* | p = 0.11 | – | – | p = 0.86 | ||||||
| Males | 12 (18%) | 1 (17%) | 11 (16%) | 1 (17%) | – | – | – | – | 1 (1%) | 0 (0%) |
| p = 0.45 | p = 0.37 | – | – | p = 0.81 | ||||||
| Females | 15 (24%) | 1 (11%) | 9 (14%) | 1 (11%) | 7 (11%) | 0 (0%) | 1 (2%) | 0 (0%) | 1 (2%) | 0 (0%) |
| p = 0.39 | p = 0.092 | p = 0.60 | NE | NE | ||||||
*Log rank test, two tailed p value.
PJS, Peutz‐Jeghers syndrome. NE, not estimable.