Table 3 Cancer risk differences in Peutz‐Jeghers syndrome patients between missense (M) versus truncating (T) mutation carriers.

Sex	No of cancers of each type (% of subgroup) by mutation type (M or T)
	All cancers			Gastrointestinal		Gynaecological		Breast		Other
	M		T	M	T	M	T	M	T	M	T
Overall	20 (21%)		4 (14%)	15 (15%)	3 (10%)	–	–	–	–	2 (2%)	0 (0%)
	p = 0.45			p = 0.40		–		–		p = 0.73
Males	9 (18%)	2 (14%)		8 (16%)	2 (14%)	–	–	–	–	1 (2%)	0 (0%)
	p = 0.66			p = 0.50		–		–		p = 0.62
Females	11 (24%)		2 (13%)	7 (15%)	1 (7%)	5 (11%)	1 (7%)	1 (2%)	0 (0%)	1 (2%)	0 (0%)
	p = 0.57			p = 0.61		p = 0.74		p = 0.72		NE

NE, not estimable.