Table 5 Spectrum of cancer associated with exon 6 mutations of the LKB1 gene in Peutz‐Jeghers syndrome patients reported in other studies.
| References | Type of mutation | Mutation | No and type of cancer |
|---|---|---|---|
| Ylikorkala, 19995 | Deletion: 773‐780del7bp | 263Fs† | 1 pancreas |
| Deletion: 747‐760del13bp | 257Fs | 1 colon | |
| Deletion: 604‐623del19bp | 248Fs | 1 ovary | |
| 1 testis | |||
| Boardman, 20006 | Insertion: 844insC | 281Fs | 1 pancreas |
| 1 prostate | |||
| 1 colon | |||
| Olschwang, 200135 | Deletion: 843delC | 281Fs | 1 pancreas |
| 1 kidney | |||
| Nakamura, 200236 | Deletion: 843delC | 281Fs | 1 duodenum |
| Lim, 20037 | Deletion: 846del | 282Fs | 2 breast |
| Takahashi, 200437 | Insertion: 757‐758insT | 252Fs | 1 Stomach |
| Amos, 200438 | Insertion: 842‐843insC | 280Fs | 2 carcinomas* |
| Present study | Deletion: 843delC | 281Fs | 1 oesophagus |
| 1 small intestine | |||
| Deletion: 263‐5delTTGT | 263Fs | 1 endometrial |
FS, frameshift.
*Organ not determined.