Table 3 Microsatellite instability status and frequency of CpG island methylator phenotype (CIMP).

MSI status	No of methylated loci						CIMP
	0	1	2	3	4	5	⩾4
MSI‐H	15	5	2	0	13	45	58/80 (73%)*†
MSI‐L	29	9	5	7	4	2	6/56 (11%)*‡
MSS	159	70	45	23	12	0	12/309 (3.9%)†‡

MSI‐H, microsatellite instability‐high; MSI‐L, microsatellite instability‐low; MSS, microsatellite stable.

*MSI‐H versus MSI‐L, p = 4×10⁻¹³; †MSI‐H versus MSS, p = 2×10⁻³⁸; ‡MSI‐L versus MSS, p = 0.04.