Table 4 KRAS and BRAF mutations, and frequency of CpG island methylator phenotype (CIMP).

KRAS	BRAF	No of methylated loci						CIMP
		0	1	2	3	4	5	⩾4
Mutant	Wild‐type	59	37	21	10	5	2	7/134 (5.2%)*†
Wild‐type	Mutant	5	2	6	7	14	29	43/63 (68%)*‡
Wild‐type	Wild‐type	107	34	17	8	8	15	23/189 (12%)†‡

*KRAS mutant versus BRAF mutant, p = 10⁻²⁰; †KRAS mutant versus both wild‐types, p = 0.05; ‡BRAF mutant versus both wild‐types, p = 6×10⁻¹⁷.