Figure 5.
Survival of wild-type, IFN receptor-deficient, and PKR-deficient mice after intracerebral infection. After intracerebral infection, survival of wild-type 129 (closed squares), IFN-αβ receptor-deficient (open diamonds), and IFN-αβγ receptor-deficient (closed diamonds) mice is shown for control virus (A) and Δ34.5 (B). Survival of wild-type 129/B6 (closed squares) and PKR-deficient (open triangles) mice is shown for control virus (C) and Δ34.5 virus (D). At least 10 mice were used over two experiments to generate the data shown. Control virus and Δ34.5 are both in the background of strain 17.
