Table 4 Univariate analysis of factors associated with clarithromycin resistance among paediatric patients not previously treated for Helicobacter pylori infection (n = 800).
| Clarithromycin | OR | 95% CI | p Value | |||
|---|---|---|---|---|---|---|
| Susceptible n = 633 | Resistant n = 167 | |||||
| Sex | Female | 364 | 76 | 1 | ||
| Male | 269 | 91 | 1.62 | (1.15 to 2.82) | 0.006 | |
| Age (years) | >11 | 275 | 56 | 1 | ||
| 6–11 | 278 | 78 | 1.38 | (0.94 to 2.02) | 0.100 | |
| <6 | 80 | 33 | 2.03 | (1.23 to 3.33) | 0.005 | |
| Country of birth | Western Europe | 437 | 134 | 1 | ||
| Eastern Europe | 88 | 14 | 0.52 | (0.29 to 0.94) | 0.031 | |
| Asia, Africa, America and Middle East | 108 | 19 | 0.57 | (0.34 to 0.97) | 0.038 | |
| Mother's country of birth | Western Europe | 258 | 94 | 1 | ||
| Eastern Europe | 98 | 19 | 0.53 | (0.31 to 0.92) | 0.023 | |
| Asia, Africa, America and Middle East | 277 | 54 | 0.54 | (0.37 to 0.78) | 0.001 | |
| Country of residence | Northern Europe | 30 | 1 (3.3%) | 1 | ||
| Southern Europe | 122 | 59 (32.5%) | 14.51 | (1.93 to 108.98) | 0.009 | |
| Eastern Europe | 47 | 10 (17.5%) | 6.38 | (0.78 to 52.44) | 0.085 | |
| Western Europe | 434 | 97 (18.2%) | 6.71 | (0.90 to 49.77) | 0.063 | |
| Country of residence | Northern, Eastern and Western Europe | 511 | 108 (17.4) | 1 | ||
| Southern Europe | 122 | 59 (32.5%) | 2.29 | (1.57 to 3.33) | <10−3 | |
| Date of investigation | ⩽1999 | 178 | 45 | 1 | ||
| 2000 | 146 | 48 | 1.30 | (0.82 to 2.06) | 0.265 | |
| 2001 | 161 | 44 | 1.08 | (0.68 to 1.72) | 0.744 | |
| ⩾2002 | 148 | 30 | 0.80 | (0.48 to 1.34) | 0.397 | |
| Peptic ulcer | No | 589 | 161 | 1 | ||
| Yes | 44 | 6 | 0.50 | (0.21 to 1.19) | 0.117 | |
p Value obtained by a univariate logistic model.