Table 3 Association between different cardiovascular risk factors and the presence of increased carotid artery intima–media thickness or stenosis in primary biliary cirrhosis.
No (%) with increased IMT* | OR | 95% CI | p Value | |
---|---|---|---|---|
Total cholesterol (mmol/l) | ||||
<6.21 (n = 66) | 6 (9) | 1 | ||
⩾6.21 (n = 37) | 5 (14) | 1.6 | 0.4 to 5.5 | 0.488 |
Age (years) | ||||
⩽60 (n = 50) | 3 (6) | 1 | ||
>60 (n = 53) | 8 (15) | 2.8 | 0.7 to 11.2 | 0.148 |
Arterial hypertension† | ||||
No (n = 72) | 7 (10) | 1 | ||
Yes (n = 31) | 4 (13) | 1.4 | 0.7 to 11.2 | 0.633 |
No (%) with carotid stenosis | OR | 95% CI | p Value | |
---|---|---|---|---|
Total cholesterol (mmol/l) | ||||
<6.21 (n = 66) | 3 (5) | 1 | ||
⩾6.21 (n = 37) | 7 (19) | 4.9 | 1.2 to 20 | 0.028 |
Age (years) | ||||
⩽60 years (n = 50) | 2 (4) | 1 | ||
>60 years (n = 53) | 8 (15) | 4.3 | 0.9 to 21 | 0.076 |
Arterial hypertension† | ||||
No (n = 72) | 2 (3) | 1 | ||
Yes (n = 31) | 8 (26) | 12.1 | 2.4 to 61 | 0.002 |
IMT, intima–media thickness; PBC, primary biliary cirrhosis.
*IMT values in the highest quintile of the distribution of carotid artery measures obtained in the subjects under study (cut‐off value for the quintile with highest thickness = 0.808 mm).
†Blood pressure values of ⩾140/90 mm Hg, or treatment for hypertension.