Table 1 Allele and genotype frequencies by phenotype*.

Phenotypes	All			IBD5risk
	n	%	Allele frequency (%)	n	%
Localisation
Ileal (1+4+5+7)	271	83.4	48.0	197	72.7
Perianal (2+4+6+7)	149	45.8	46.6	109	73.2
Colon (3+5+6+7)	160	49.2	47.5	116	72.5
				†
One location
1 Ileal only	101	31.1	44.1	67	66.3
2 Perianal only	10	3.1	20.0	4	40.0
3 Colon only	27	8.3	46.3	20	74.1
Two locations
4 Ileal+perianal	54	16.6	50.9	43	79.6
5 Ileal+colon	48	14.8	49.0	34	70.8
6 perianal+colon	17	5.2	32.4	9	52.9
Three locations
7 Ileal+perianal+colon	68	20.9	50.7	53	77.9
				p = 0.06
Behaviour
Inflammatory	71	21.8	38.0	44	62.0
Fistulising only	47	14.5	57.4	42	89.4
Stenotic only	63	19.4	50.8	46	73.0
Fistulising/stenotic	144	44.3	44.4	98	68.1
				p = 0.01
Sex
Female	230	70.8	45.2	160	69.6
Male	95	29.2	48.4	70	73.7
				p = 0.46
Smoking
Ever‐smokers	167	51.4	43.4	111	66.5
Never‐smokers	158	48.6	49.1	119	75.3
				p = 0.08
Age of onset
<17	55	16.9	51.2	41	74.6
17–40	259	79.7	45.6	184	71.0
>40	11	3.4	31.8	5	45.4
				p = 0.15
Smoking
Age at onset, mean (SD)	23.4 (7.8)			22.8 (7.5)
All	325	100.0	46.2	230	70.8

*The p values refer to Pearson's χ² test comparing counts within boxes.

†These categories are not mutually exclusive and therefore were not compared.