Figure 6 Veratridine‐stimulated electrogenic secretion in the colon during ileitis. (A) Representative trace depicting the Isc response to application of veratridine (30 μM) to the serosal compartment of the Ussing chamber. The response slowly desensitises and is abolished by the addition of TTX (300 nM) to the serosal bath. (B) Comparison of Isc responses of control and ileitis colonic mucosa to addition of veratridine. Ileitis results in a significantly reduced effect of veratridine in the colon. *p<0.05 (mean (SE)).