Table 1 Electrophysiological characteristics of colonic S neurones.
Control | Ileitis | |
---|---|---|
RMP (mV) | −49.2 (1.6) | −48.9 (1.5) |
Input resistance (MΩ) | 220 (19) | 198 (25) |
AP threshold (pA) | 108 (20) | 122 (23) |
APs at rheobase | 1.6 (0.2) | 1.2 (0.3) |
APs at 2×rheobase | 6.2 (1.2) | 5.6 (1.0) |
Maximum APs | 13.6 (2.5) | 12.3 (2.4) |
AP amplitude (mV) | 59 (1.9) | 65 (4) |
APD50 (ms) | 1.53 (0.05) | 1.70 (0.09) |
Fast EPSP amplitude (mV) | 21.6 (1.5) | 28.2 (1.12)* |
Hexamethonium‐resistant | 1.7 (0.5) | 9.8 (1.3)* |
fast EPSP amplitude (mV) | ||
Slow EPSP amplitude (mV) | 4.8 (0.9) | 10.95 (2.0)* |
Mean (SE) data are shown (*p<0.05). n = 24 for control neurones and n = 24 ileitis neurones.