Figure 4 Correlation of artemin with pathomorphological inflammatory changes in chronic pancreatitis (n = 66). Transcript numbers are presented on a logarithmic scale. The horizontal bars represent the median values and the error bars IQR. (A) Expression of artemin mRNA transcripts was positively related to the severity of inflammation in chronic pancreatitis (p<0.03). (B) The activity of inflammation did not correlate with artemin expression. (C) Artemin mRNA expression was positively related to the severity of perineural inflammation (p<0.04). (D) Glial derived neurotrophic factor family receptor (GFR)α3 mRNA expression showed a tendency to increase with the severity of perineural inflammation but failed to reach statistical significance.