Table 2 Human ocular expression of TLRs.
Ocular tissue | Cell type | TLR* |
---|---|---|
Cornea | Corneal epithelium | TLR1, 2†, 3, 4†, 5†, 6, 7, 9, 1013,14,17 |
Cultured corneal epithelial cells | TLR1, 2†, 3†, 4†, 5†, 6, 911,12,13,14,17 | |
Cultured corneal fibroblasts | TLR419 | |
Conjunctiva | Whole bulbar conjunctiva | TLR428 |
Uvea | Resident stromal APCs | TLR4†28,31 |
Cultured iris endothelial cells | TLR431 | |
Retina | Whole retina | TLR428 |
Cultured RPE cells | TLR1, 2†, 3†, 4†, 5, 6, 7, 9, 1035,40 | |
Sclera | Whole sclera | TLR428 |
APCs, antigen presenting cells; RPE cells, retinal pigment epithelial cells.
*mRNA expression only, unless otherwise specified.
†TLR protein expression confirmed.