Frucht‐Pery et al9
|
Corneal intraepithelial neoplasia |
3 |
0.02% MMC four times daily for 10–22 days |
|
Conjuntival hyperaemiaOcular pain |
32 |
|
|
|
|
|
Blepharospasm |
1 |
Frucht‐Pery et al1
|
Conjunctival‐corneal intraepithelial neoplasia |
17 |
0.02–0.04% MMC four times daily for 7–28 days |
|
Ocular painConjunctival hyperaemia |
28 |
|
|
|
|
|
blepharospasm |
1 |
|
|
|
|
|
Allergy (probable) |
2 |
Heigle et al3
|
Recurrent conjunctival epithelial neoplasia |
3 |
0.04% three times daily for 3 weeks, 1 week on/1 week off |
|
Corneal oedema and epithelial toxicity |
1 |
Wilson et al4
|
Conjunctival and corneal epithelial dysplasia and neoplasia |
7 |
0.04% MMC four times daily for 4–21 days, in alternate weeks |
|
Conjunctival inflammationOcular painPunctate epithelial keratopathy |
572 |
Finger et al6
|
Conjunctival melanoma and PAM with atypia |
10 |
0.04% MMC qid for 28 days (4) and 7 days (6) |
|
KeratoconjunctivitisCorneal haze |
101 |
Demirci et al7
|
Conjunctival malignant melanoma and PAM with atypia |
12 |
0.04% four times daily for 28 days (7) |
|
Keratoconjunctivitis |
12 |
|
|
|
0.04% four times daily for 7 days (5) |
|
Focal corneal haze |
1 |
Daniell et al2
|
Corneal conjunctival intraepithelial neoplasia |
20 |
0.02–0.04% MMC four times daily for 1–5 weeks, 1 week on/1 week off |
|
Epithelial toxicityContact dermatitisDisciform keratitis |
1021 |
|
|
|
|
|
Membranous conjunctivitis |
1 |
Shields et al10
|
Diffuse conjunctival corneal squamous cell carcinoma |
10 |
0.04% MMC four times daily for 1–4 weeks, 1 week on/1 week off |
|
Conjunctival erythemaConjunctival irritationConjunctival chemosis |
632 |
|
|
|
|
|
Punctate keratopathy |
1 |
Shields et al8
|
Sebaceous gland carcinoma with conjunctival pagetoid spread |
4 |
0.04% MMC four times daily for 1–4 weeks, 1 week on/1 week off |
|
Ocular painConjunctival irritationConjunctival injection |
134 |
|
|
|
|
|
Recurrent corneal abrasion |
1 |
|
|
|
|
|
Peripheral corneal pannus |
1 |
Sacu et al12
|
Conjunctival malignant melanoma |
1 |
0.04% MMC four times daily for 8 weeks, two 28 days courses, separated by 1 month |
|
Intumescent cataract |
1 |
Billing et al13
|
Corneal epithelial dysplasia |
1 |
0.04% MMC four times daily for 2 weeks, 1 week on/1 week off |
|
Punctal canalicular stenosis |
1 |
Dudney et al11
|
Conjunctival corneal intraepithelial neoplasia |
1 |
0.04% MMC four times daily for 5 weeks, five 1 week courses |
|
Recurrent non‐healing corneal epithelial defects/limbal stem cell deficiency |
1 |
Kopp et al14
|
MM, PAM, SCC |
14 |
0.04% MMC four times daily for 2–18 weeks, one to six 2 week courses |
|
Punctal canalicular stenosis |
6 |