Table 2 Treatment and outcome of 10 primary lacrimal sac lymphomas in a predominantly white population.
Case | Diagnosis | Treatment | Ann Arbor stage of disease (diagnosis → follow up → last follow up) | Follow up period (years) | Alive/dead (years after diagnosis) | ||
---|---|---|---|---|---|---|---|
A | DLBCL | Palliative RT | Not investigated because of old age | None | DOD (1) | ||
B | DLBCL | Surgery + CHOP × 3 + RT 30 Gy | I → NA | NA | NA | ||
E | DLBCL | CHOP × 4 + RT 40 Gy | I → CR | 5 | Alive (5) | ||
F | MALT | Incomplete excision. Refused further treatment | I → I | 1 | Alive (1) | ||
G | MALT | Surgery + RT regional and other LN, 40 Gy + CHOP × 6 | I → IV | 7 | Dead, cause unknown (10) | ||
J | MALT | RT 45 Gy | I → CR | 12 | Alive (12) | ||
K | Transitional MALT | Rituximab dose NA | I → II → CR | 2 | NA | ||
L | Transitional MALT | Surgery + CHOP × 3 | II* → IV | 3 | DOD (3) | ||
N | B cell, unclassified | RT dose NA | I → NA | NA | NA | ||
O | B cell, unclassified | CHOP × 3 + RT 40 Gy | I → CR | NA | NA |
CHOP, cyclophosphamide + hydroxydoxorubicine + oncovine + prednisone; CR, complete remission; DLBCL, diffuse large B cell lymphoma; DOD, dead of disease; Gy, Gray; LN, lymph nodes; MALT, extranodal marginal zone B cell lymphoma of mucosa associated lymphoid tissue; NA, not available; RT, radiation therapy.
*This patient had symptoms from the lacrimal sac more than 6 months before diagnosis was made.