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. 2006 Aug;90(8):994–998. doi: 10.1136/bjo.2006.090738

Table 1 Comparison of the ultrasonographic (US) and demographic characteristics of clinically suspicious naevi.

Clinically suspicious naevi characteristic Benign naevi (n = 148) Premalignant naevi (n = 17) p Value benign v premalignant
Which eye (% of naevi in the left eye) 43.2% 54.5% p = 0.5 (χ2 test)
Location in the eye Posterior pole 57.6% 70.6% p = 0.44 (χ2 test)
Superior retina 47.0% 56.3% p = 0.64 (χ2 test)
Nasal retina 33.3% 50% p = 0.27 (χ2 test)
First US examination Thickness (mm (SD*)) 1.74 (0.53) 2.19 (0.40) p = 0.001 (t test)
Largest base diameter (mm (SD)) 6.1 (2.0) 7.1 (1.9) p = 0.05 (t test)
Base area (mm2 (SD)) 27.2 (16.3) 34.0 (13.9) p = 0.1 (t test)
Internal reflectivity (% (SD)) 71.2 (15.8) 57.5 (24.3) P = 0.002 (t test)
Last US examination Thickness (mm (SD)) 1.49 (0.56) 2.85 (0.92) p<0.0001 (t test)
Largest base diameter (mm (SD)) 6.4 (2.1) 7.6 (3.0) p = 0.03 (t test)
Base area (mm2 (SD)) 32.1 (19.4) 53.6 (26.7) p = 0.0001 (t test)
Internal reflectivity (% (SD)) 72.6 (18.0) 40.8 (18.1) p<0.0001 (t test)
p Value (last v first US examination) t test Thickness p = 0.0001 p = 0.009
Largest base diameter p = 0.2 p = 0.56
Base area p = 0.02 p = 0.01
Internal reflectivity p = 0.47 p = 0.03

*SD, standard deviation.