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. 2007 Apr 26;104(18):7664–7669. doi: 10.1073/pnas.0607713104

Fig. 4.

Fig. 4.

CCD images of Per1-luc rhythms in single SCN cells. (A) Representative CCD images from the anterior and posterior SCN in different photoperiods. Single SCN cells indicated by colored circles correspond to cells with the number in the same color in Fig. 4B. (Scale bar: 100 μm.) (B) Serial demonstration of bioluminescence in a single cell at 1-h intervals on day 1. In LD18:6 (Upper), bioluminescence is strong either at the early or late subjective day in the anterior SCN, whereas it is strong at the middle of subjective day in the posterior. In LD6:18 (Lower), individual rhythms are essentially the same between the anterior and posterior SCN with respect to circadian phase. (Scale bar, 10 μm.) A, anterior; P, posterior; L, left; R, right. AM and AE, cells with morning and evening peaks for the anterior SCN in LD18:6, respectively. Gray and black horizontal bars, the subjective day and night, respectively.