Table 1.
Specific Activity [nmoles min−1mg−1]1 | ||||
---|---|---|---|---|
Product | AKR1C1 | AKR1C2 | AKR1C3 | AKR1C4 |
3α-Diol | 2.8 | 75.6 | 2.7 | 102.0 |
3β-Diol | 12.4 | 4.4 | 2.0 | 29.8 |
Assayed with 40 μM 5α-DHT plus 180 μM NADPH at 37°C. From Steckelbroeck et al. 2004.
Specific Activity [nmoles min−1mg−1]1 | ||||
---|---|---|---|---|
Product | AKR1C1 | AKR1C2 | AKR1C3 | AKR1C4 |
3α-Diol | 2.8 | 75.6 | 2.7 | 102.0 |
3β-Diol | 12.4 | 4.4 | 2.0 | 29.8 |
Assayed with 40 μM 5α-DHT plus 180 μM NADPH at 37°C. From Steckelbroeck et al. 2004.