TABLE 1.
Subject characteristics1
| Characteristics | Value |
|---|---|
| Sex | |
| Females (n) | 42 |
| Males (n) | 47 |
| Glucose tolerance | |
| Normal (n) | 60 |
| Impaired (n) | 29 |
| Age (y) | 29 ± 7 (18–44)2 |
| Height (cm) | 167 ± 7 (152–183) |
| Body weight (kg) | 93 ± 20 (55–137) |
| Percentage body fat (%) | 33 ± 7 (14–46) |
| Fat-free mass (kg) | 61 ± 11 (41–85) |
| Fasting glucose (mg/dL) | 87 ± 9 (64–116) |
| 2-h OGTT (mg/dL) | 121 ± 30 (51–197) |
| Fasting insulin (μU/mL) | 44 ± 18 (13–112) |
| TSH (μIU/mL) | 2.75 ± 1.69 (0.35–8.94) |
| Free T3 (pg/mL) | 2 ± 0.4 (1–2.94) |
| Free T4 (ng/dL) | |
| Males | 1.3 ± 0.3 (0.78–1.97) |
| Females | 1.1 ± 0.2 (0.71–1.55) |
| Leptin (ng/mL) | |
| Males | 9.6 ± 4.9 (1.8–21.2) |
| Females | 28.9 ± 10.6 (4.4–45.7) |
| 24-h Energy expenditure (kcal/d) | 2340 ± 385 (1545–3332) |
| Sleeping metabolic rate (kcal/d)3 | 1642 ± 230 (1164–2164) |
| 24-h Respiratory quotient | 0.85 ± 0.02 (0.8–0.9) |
| 24-h Carbohydrate oxidation (kcal/d) | 1113 ± 219 (549–1677) |
| 24-h Lipid oxidation (kcal/d) | 936 ± 267 (431–1729) |
| 24-h Energy balance (kcal/d) | −162 ± 222 (−745 to 286) |
| 24-h Carbohydrate balance (kcal/d) | −23 ± 163 (−414 to 503) |
| 24-h Fat balance (kcal/d) | −282 ± 236 (−1069 to 149) |
| 24-h Protein balance (kcal/d) | 164 ± 99 (−58 to 475) |
1
n = 89. TSH, thyroid-stimulating hormone; OGTT, oral-glucose-tolerance test; T3, triiodothyronine; T4, thyroxine. Insulin (μUI/mL), glucose (mg/dL), TSH (μIU/mL), free T3 (pg/mL), and free T4 (ng/dL) concentrations are given in conventional units; to convert to SI units (pmol/L, mmol/L, μIU/L, pmol/L, and pmol/L, respectively), multiply by 6.945, 0.055, 1, 1.54, and 12.87, respectively.
2
x̄ ± SD; range in parentheses (all such values).
3
Data available for 86 subjects.