Figure 3.
Various LO products (A) and anandamide (B) in activating icap in inside-out patches of cultured dorsal root ganglion neurons. (C) A summary of effects of various LO products on activating icap. Relative channel activities of each 10 μM LO product are normalized to the channel activity (NPo) obtained with 10 μM 12-(S)-HPETE. DiHETE, 8-(R)-15-(S)-dihydroxyeicosatetraenoic acid; Hepox. A3 or B3, hepoxilin A3 or B3. Numbers above the bars represent the number of experiments. *, P < 0.05; **, P < 0.01; and ***, P < 0.001 compared with NPo of 12-(S)-HPETE.