Table 3 Comparison of mean blood flow velocities (cm/s) in patients with diabetes before and after atorvastatin and placebo treatment.
Group 1 (n = 15) | Group 2 (n = 15) | Group 3 (n = 15) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
NPDR (n = 8) | PDR (n = 7) | |||||||||||
Baseline | After 10 weeks | p Value* | Baseline | After 10 weeks | p Value* | Baseline | After 10 weeks | p Value* | Baseline | After 10 weeks | p Value* | |
OA | ||||||||||||
PSV | 32.5 (5.8) | 29.5 (5.0) | 0.053 | 30.0 (7.1) | 25.2 (5.6) | 0.007† | 33.6 (6.5) | 32.6 (6.7) | 0.57 | 30.5 (5.7) | 31.1 (5.5) | 0.81 |
EDV | 6.7 (1.4) | 6.5 (1.1) | 0.32 | 6.3 (1.3) | 6.1 (1.4) | 0.43 | 6.7 (1.2) | 6.6 (1.1) | 0.52 | 6.3 (1.6) | 6.3 (1.4) | 0.91 |
RI | 0.80 (0.06) | 0.77 (0.05) | 0.12 | 0.79 (0.05) | 0.77 (0.04) | 0.06 | 0.78 (0.06) | 0.79 (0.06) | 0.62 | 0.80 (0.06) | 0.79 (0.05) | 0.67 |
CRA | ||||||||||||
PSV | 11.3 (1.9) | 9.5 (1.4) | 0.002† | 9.2 (2.0) | 7.8 (1.6) | 0.01† | 10.5 (2.1) | 10.4 (2.0) | 0.90 | 9.2 (1.9) | 9.3 (2.0) | 0.67 |
EDV | 3.4 (0.7) | 3.5 (0.5) | 0.78 | 3.0 (0.6) | 3.0 (0.4) | 0.75 | 3.3 (0.4) | 3.4 (0.5) | 0.66 | 3.1 (0.5) | 3.0 (0.4) | 0.76 |
RI | 0.69 (0.06) | 0.62 (0.06) | 0.003† | 0.66 (0.08) | 0.61 (0.08) | 0.01† | 0.68 (0.07) | 0.69 (0.07) | 0.88 | 0.66 (0.08) | 0.67 (0.07) | 0.90 |
CRA, central retinal artery; EDV, end diastolic velocity; NPDR, non‐proliferative diabetic retinopathy; OA, Opthalmic artery; PDR, proliferative diabetic retinopathy; PSV, Peak systolic velocity; RI, resistive index.
Values are mean (SD).
* p Value for comparison before and after atorvastatin and placebo treatment.
† Statistically significant.