Skip to main content
. 2006 Sep 13;91(2):199–203. doi: 10.1136/bjo.2006.102848

Table 2 Summary of changes in best‐corrected visual acuity.

Mean value for each dosage group 4 mg (n = 23) SD 8 mg (n = 20) SD p Value
Baseline BCVA (ETDRS logMar units) (approx Snellen equivalent) 0.81 (20/130) 0.26 0.79 (20/125) 0.3 0.81
BCVA at 2 weeks 0.71 0.26 0.65 0.31 0.49
BCVA at 4 weeks 0.66 0.28 0.62 0.26 0.57
BCVA at 9 weeks 0.70 0.28 0.61 0.27 0.26
BCVA at 17 weeks 0.69 0.26 0.60 0.26 0.23
BCVA at 26 weeks (Approx Snellen equivalent) 0.75 (20/110) 0.29 0.59 (20/80) 0.27 0.078
BCVA improvement at 2 weeks (number of ETDRS letters) 4.9 8.7 6.8 9.4 0.5
BCVA improvement at 4 weeks 7.3* 10.3 8.7 10.5 0.67
BCVA improvement at 9 weeks 5.4 8.3 9.2 10.5 0.19
BCVA improvement at 17 weeks 6.0 9.3 9.7 10.4 0.22
BCVA improvement at 26 weeks 3.1 10 9.9* 11.7 0.047
Number (proportion) of eyes with BCVA improvement of ⩾15 ETDRS letters at 6 months 3 (13%) 6 (30%) 0.26
Number (proportion) of eyes with BCVA deterioration of ⩾15 ETDRS letters at 6 months 2 (8%) 1 (5%) 1.0

BCVA, best‐corrected visual acuity; ETDRS, Early Treatment of Diabetic Retinopathy Study; logMar, logarithm of minimum angle of reolution.

*Best BCVA improvement within group.