Figure 3.

Effects of GROβ and GluR agonists on granule cell survival. Cultured neurons were treated for 24 h with vehicle (C), 60 nM GROβ, 10 μM AMPA, 100 μM NMDA, or 60 nM GROβ + 10 μM AMPA, in 5 mM K⁺-containing medium, as described in the legend to Fig. 1. Data expressed as in Fig. 1 are the mean ± SEM of at least six independent experiments. Student's t test: *, P < 0.001.