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. Author manuscript; available in PMC: 2007 May 1.
Published in final edited form as: Carcinogenesis. 2006 Dec 20;28(5):940–946. doi: 10.1093/carcin/bgl249

Figure 4.

Figure 4

(A) Gene expression analysis from liver tissue in 3-month-old (3mo) and 12-month-old (12mo) wild-type and Fxr-null mice. IL-1β, C-Myc, β-catenin and PCNA mRNA expression was assessed by qPCR. Expression was normalized to β-actin and each bar represents the mean value ± S.D. (*)= p < 0.05 compared to livers from age-matched wild-type controls. (B) Western blot analysis of c-myc and β-catenin was performed using total protein extract from livers without macroscopic gross lesions. GAPDH was used as an equal loading control. Bars at the right side indicate positions of size markers (Bio-rad Pre-stained SDS-PAGE standard low range).