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. Author manuscript; available in PMC: 2007 May 1.
Published in final edited form as: Carcinogenesis. 2006 Dec 20;28(5):940–946. doi: 10.1093/carcin/bgl249

Table 1.

Incidence of liver lesions

Strain Gender Mice # Preneoplastic foci (%) Adenoma HCC Mixed HCC Total tumor incidence
WT Male 16 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
Female 16 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
Total 32 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
Fxr-null Male 31 19 (61)** 10 (32)* 2 (6.5) 3 (9.7) 10 (32)*
Female 22 15 (68)** 9 (41)* 1 (4.5) 2 (9.1) 10 (45)**
Total 53 34 (64)** 19 (36)** 3 (5.7) 5 (9.4) 20 (38)**

HCC; Hepatocellular carcinoma

*

P<0.05 compared with different genotype

**

P<0.05 compared with different genotype

No difference was seen among the different genders