Table 2.
Compda | R1 | R3 | IC50 | Ecb | Sac |
---|---|---|---|---|---|
19 | H | 8 | 16 | 4 | nd |
12 | 8 | 10 | 1 | 2 | |
20 | 9 | 7 | 2 | 16 | |
21 | 10 | 3 | 4 | 8 | |
22 | 8 | 10 | 4 | 8 | |
23 | 9 | 18 | 16 | 32 | |
24 | 10 | 1 | 16 | 8 | |
25 | 8 | 8 | 2 | 8 | |
26 | 8 | 8 | 2 | 4 | |
27 | 9 | 11 | 8 | 16 | |
28 | 10 | 1 | 16 | 8 | |
29 | 8 | 10 | 4 | 2 | |
30 | 9 | 12 | 8 | 32 | |
31 | 10 | 13 | 32 | 2 | |
32 | 8 | 19 | 4 | 8 | |
33 | 9 | 13 | 16 | 32 | |
34 | 10 | 15 | 16 | 8 | |
35 | 8 | 10 | 8 | 16 | |
36 | 9 | 19 | 16 | 32 | |
37 | 10 | 21 | 16 | 8 | |
38 | 8 | 17 | 2 | 8 | |
39 | 9 | 40 | 8 | 64 | |
40 | 10 | 17 | 16 | 16 | |
41 | 8 | 310 | 16 | 16 | |
42 | 9 | 40 | 64 | 32 | |
43 | 10 | 44 | 16 | 8 | |
44 | 8 | 21 | 4 | 16 | |
45 | 9 | 31 | 32 | 32 | |
46 | 10 | 27 | 32 | 16 | |
47 | 8 | 72 | 16 | 32 | |
48 | 9 | 77 | 32 | 64 | |
49 | 10 | 43 | 32 | 32 | |
50 | 9 | 58 | 16 | 16 | |
51 | 10 | 36 | 32 | 16 | |
52 | 9 | 14 | 8 | nd | |
53 | 10 | 11 | 16 | 16 | |
54 | 9 | >1000 | nd | nd | |
55 | 10 | >1000 | nd | nd | |
Cm | 1.5 | 4 | 8 |
nd, not determined.
Cm, chloramphenicol.
E. coli ATCC 25922 minimum inhibitory concentration (μg/mL)4
S. aureus ATCC 25923 (MIC).