Table 3.
Contrasts comparing the average gene expression levels in brain between groups of foxes.
| Contrast | Gene | Fold Change | p-value |
| 1) S vs NSa | HBE* | -3.1 | 0.005 |
| HBB | -2.3 | 0.002 | |
| HBA | -2.2 | 0.048 | |
| HEBP1* | -1.5 | 0.022 | |
| 2) Cross vs parentalb | HBE | -1.2 | 0.623 |
| HBB | 1.4 | 0.132 | |
| HBA | 1.2 | 0.617 | |
| HEBP1 | -1.1 | 0.365 | |
| 3) Wild vs Farm | HBE* | 2.7 | 0.008 |
| HBB | 1.0 | 0.853 | |
| HBA | -1.9 | 0.059 | |
| HEBP1* | -1.3 | 0.143 |
a = test of composite additive genetic effect.
b = test for composite genetic dominance effect.
* = previously reported in Lindberg et al [11].
The three contrasts tests the following mRNA differences: 1) difference between selected and non-selected farm foxes, 2) difference between off-spring from crossing and back crossing S and NS with the weighted average of the parental S and NS lines, and 3) difference between the average of farmed foxes (S, NS and Cross) and wild red foxes.